Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
AFE_0774Phosphorylase, putative. (333 aa)    
Predicted Functional Partners:
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Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
 
     0.817
AFE_0771
Identified by match to protein family HMM PF02133; Belongs to the purine-cytosine permease (2.A.39) family.
 
     0.815
AFE_0778
Conserved domain protein.
 
     0.778
AFE_0772
Guanine deaminase, putative; Identified by similarity to SP:P76641; match to protein family HMM PF01979.
 
     0.676
AFE_0779
Cyanuric acid amidohydrolase; Cyclic amide hydrolase of unknown substrate specificity. Catalyzes the hydrolytic ring-opening of a cyclic amide. Does not act on cyanuric acid nor barbituric acid.
 
     0.668
AFE_0775
Xanthine dehydrogenase, molybdenum-binding subunit, putative; Identified by similarity to SP:Q46799; match to protein family HMM PF01315; match to protein family HMM PF02738.
 
     0.663
AFE_0777
Xanthine dehydrogenase, FAD-binding protein, putative; Identified by similarity to SP:Q8X6C5; match to protein family HMM PF00941.
 
     0.639
AFE_0763
TonB-dependent receptor, putative; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
 
     0.615
AFE_0780
Xanthine dehydrogenase accessory factor, putative; Identified by similarity to GB:CAB41849.1; match to protein family HMM PF02625.
 
     0.611
AFE_3229
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.589
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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