Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0782Amidohydrolase, AtzE family; Identified by match to protein family HMM PF01425; match to protein family HMM TIGR02715. (465 aa)    
Predicted Functional Partners:
gatB
glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
 
 
 0.991
AFE_0779
Cyanuric acid amidohydrolase; Cyclic amide hydrolase of unknown substrate specificity. Catalyzes the hydrolytic ring-opening of a cyclic amide. Does not act on cyanuric acid nor barbituric acid.
    
  0.972
gatC
glutamyl-tRNA(Gln)/aspartyl-tRNA(Asn) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
 
 
 0.971
AFE_0783
Conserved hypothetical protein; Identified by similarity to PIR:AD0396.
 
    0.916
ggt
Gamma-glutamyltranspeptidase; Identified by match to protein family HMM PF01019; match to protein family HMM TIGR00066.
 
  
 0.826
AFE_0781
Conserved hypothetical protein.
       0.777
AFE_0784
Hypothetical protein; Identified by glimmer; putative.
       0.770
AFE_0780
Xanthine dehydrogenase accessory factor, putative; Identified by similarity to GB:CAB41849.1; match to protein family HMM PF02625.
       0.732
AFE_0777
Xanthine dehydrogenase, FAD-binding protein, putative; Identified by similarity to SP:Q8X6C5; match to protein family HMM PF00941.
  
    0.682
AFE_0775
Xanthine dehydrogenase, molybdenum-binding subunit, putative; Identified by similarity to SP:Q46799; match to protein family HMM PF01315; match to protein family HMM PF02738.
       0.678
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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