Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0791Na+/H+ antiporter, putative; Identified by match to protein family HMM PF00999. (448 aa)    
Predicted Functional Partners:
AFE_0795
Conserved hypothetical protein; Identified by similarity to GB:AAM43220.1.
 
     0.815
AFE_0794
Conserved hypothetical protein; Identified by similarity to GB:CAD13953.1.
 
     0.810
AFE_0793
3-oxoacyl-(acyl-carrier-protein) reductase, putative; Identified by similarity to SP:P70720; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.777
AFE_0796
3-oxoacyl-(acyl-carrier-protein) synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
     0.768
AFE_1968
Potassium-efflux system protein; Identified by match to protein family HMM PF00999; match to protein family HMM PF02080; match to protein family HMM PF02254; match to protein family HMM TIGR01409; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.622
AFE_0797
Acyl carrier protein, putative; Identified by similarity to SP:O67611.
 
     0.561
AFE_0788
Non-heme halogenase, putative; Identified by similarity to GB:AAK81830.1; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF04820.
 
    0.553
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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