Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0795Conserved hypothetical protein; Identified by similarity to GB:AAM43220.1. (271 aa)    
Predicted Functional Partners:
AFE_0794
Conserved hypothetical protein; Identified by similarity to GB:CAD13953.1.
 
   
 0.953
AFE_0793
3-oxoacyl-(acyl-carrier-protein) reductase, putative; Identified by similarity to SP:P70720; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   0.949
AFE_0796
3-oxoacyl-(acyl-carrier-protein) synthase, putative; Identified by match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
     0.943
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.943
AFE_0797
Acyl carrier protein, putative; Identified by similarity to SP:O67611.
 
 
 0.941
AFE_0791
Na+/H+ antiporter, putative; Identified by match to protein family HMM PF00999.
 
     0.815
AFE_0802
Identified by match to protein family HMM PF00501.
 
   
 0.805
AFE_0800
Conserved hypothetical protein; Identified by similarity to GB:CAD13959.1.
 
    0.803
AFE_0798
Membrane protein, putative.
 
     0.801
AFE_0799
Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
     0.801
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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