Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0827ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224. (526 aa)    
Predicted Functional Partners:
AFE_3194
ATP-dependent DNA helicase RecG domain protein; Identified by similarity to SP:O50224; match to protein family HMM PF04326.
  
  
 
0.929
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
  0.900
AFE_0828
Conserved hypothetical protein; Identified by similarity to GB:AAM31899.1.
 
     0.855
AFE_0826
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
     0.803
AFE_0829
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
       0.774
AFE_2380
Conserved domain protein; Identified by similarity to GB:AAO78433.1.
 
     0.641
AFE_0824
Conserved hypothetical protein.
 
     0.575
AFE_0825
Hypothetical protein; Identified by glimmer; putative.
       0.566
AFE_0831
Hypothetical protein; Identified by glimmer; putative.
       0.541
AFE_0822
Hypothetical protein; Identified by glimmer; putative.
       0.424
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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