Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0829Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420. (409 aa)    
Predicted Functional Partners:
AFE_0826
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
   0.975
AFE_2372
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497.
 
   0.853
AFE_2793
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
   0.850
AFE_0828
Conserved hypothetical protein; Identified by similarity to GB:AAM31899.1.
  
    0.843
AFE_0841
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.842
AFE_0827
ATP-dependent DNA helicase, putative; Identified by similarity to SP:O50224.
       0.774
AFE_1415
Conserved domain protein; Identified by similarity to GB:BAC17067.1.
 
   0.747
AFE_0684
Type I restriction-modification system, M subunit; Identified by similarity to SP:Q47282; match to protein family HMM PF02384.
 
   0.726
AFE_2790
Type I restriction-modification enzyme, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.716
AFE_1577
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
   0.711
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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