Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0842Conserved hypothetical protein; Identified by similarity to PIR:B82823; match to protein family HMM PF01863. (111 aa)    
Predicted Functional Partners:
AFE_0841
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
     0.875
AFE_0840
Hypothetical protein; Identified by glimmer; putative.
 
     0.779
AFE_0760
Conserved hypothetical protein; Identified by similarity to PIR:A64695; match to protein family HMM PF01863.
  
     0.697
AFE_0826
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
     0.535
AFE_0839
Hypothetical protein; Identified by glimmer; putative.
       0.531
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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