Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0850Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (155 aa)    
Predicted Functional Partners:
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
 
 
 
 0.973
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
 
 
 0.939
ftsW
Cell division protein FtsW; Identified by similarity to SP:P16457; match to protein family HMM PF01098; match to protein family HMM TIGR02614; Belongs to the SEDS family.
   
 
 0.840
kdsA
3-deoxy-8-phosphooctulonate synthase; Identified by similarity to SP:O66496; match to protein family HMM PF00793; match to protein family HMM TIGR01362; Belongs to the KdsA family.
  
    0.826
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.812
ftsI
Peptidoglycan synthetase FtsI; Identified by similarity to SP:P04286; match to protein family HMM PF00905; match to protein family HMM PF03717.
  
 
 0.810
AFE_2895
Peptidoglycan synthetase FtsI, putative; Identified by similarity to SP:P04286; match to protein family HMM PF00905; match to protein family HMM PF03717.
  
 
 0.810
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
   
 
 0.807
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
    0.806
sspB
Identified by similarity to SP:P25663; match to protein family HMM PF04386.
  
     0.728
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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