Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0859Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. (403 aa)    
Predicted Functional Partners:
AFE_0710
Iron-sulfur cluster-binding protein, Rieske family; Identified by match to protein family HMM PF00355; match to protein family HMM PF01106.
  
 
 0.938
fdx
Ferredoxin, 2Fe-2S; Identified by similarity to SP:P25528; match to protein family HMM PF00111; match to protein family HMM TIGR02007.
  
 
 0.926
AFE_1541
Ferredoxin, putative; Identified by similarity to SP:P44428; match to protein family HMM PF00111.
     
  0.900
sreB
Sulfur reductase, iron-sulfur binding subunit; Identified by similarity to GB:CAC86938.1; match to protein family HMM PF00037.
   
 
 0.863
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
  
 0.848
AFE_0860
Iron-sulfur cluster-binding protein/oxidoreductase, FAD/NAD-binding; Identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970.
  
  
 0.796
AFE_0861
Globin domain protein; Identified by match to protein family HMM PF00042; Belongs to the globin family.
  
  
 0.774
AFE_0858
Conserved hypothetical protein; Identified by similarity to GB:CAE33148.1.
       0.664
AFE_2256
Identified by match to protein family HMM PF00753.
  
  
 0.549
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
  
 0.534
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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