Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_0862Drug resistance transporter, putative; Identified by match to protein family HMM PF00529. (387 aa)    
Predicted Functional Partners:
AFE_0864
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
   0.961
AFE_0863
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
   0.943
AFE_0040
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690.
 
   0.836
AFE_0171
Drug resistance transporter,putative, EmrB/QacA subfamily; Identified by match to protein family HMM PF07690.
 
   0.834
AFE_2091
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
   0.834
AFE_2184
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
   0.834
AFE_2349
Multidrug resistance protein; Identified by similarity to SP:P27304; match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
   0.834
AFE_1797
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily.
 
   0.833
AFE_0039
RND efflux system, drug efflux transporter, outer membrane lipoprotein; Identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845.
 
   0.761
AFE_2690
Type I secretion outer membrane protein, putative; Identified by match to protein family HMM PF02321.
 
   0.667
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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