Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
AFE_0870Addiction module toxin, Txe/YoeB family; Identified by similarity to GB:CAD85263.1; match to protein family HMM TIGR02116. (87 aa)    
Predicted Functional Partners:
AFE_0869
Addiction module antitoxin, Axe family; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
 
 0.981
AFE_0094
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
 
 0.629
AFE_0889
Stability protein StbD, putative; Identified by similarity to GB:AAC84003.1; match to protein family HMM PF02604.
  
 
 0.629
AFE_3268
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
 
 0.629
lon-2
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.481
AFE_0871
Heat shock protein, Hsp20 family; Identified by similarity to GB:CAE31747.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
       0.441
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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