Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
AFE_0871Heat shock protein, Hsp20 family; Identified by similarity to GB:CAE31747.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family. (134 aa)    
Predicted Functional Partners:
AFE_1648
Heat shock protein, Hsp20 family; Identified by similarity to SP:Q06823; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
  
  
  0.963
AFE_2086
Heat shock protein, Hsp20 family; Identified by similarity to GB:AAC44757.1; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.923
lon-2
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.822
clpA
ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to SP:P15716; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family.
  
 
 0.694
clpB
clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.694
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P06711; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
    
 
 0.502
AFE_0869
Addiction module antitoxin, Axe family; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.441
AFE_0870
Addiction module toxin, Txe/YoeB family; Identified by similarity to GB:CAD85263.1; match to protein family HMM TIGR02116.
       0.441
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
  
 
 0.437
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 
 0.424
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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