Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0878Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. (170 aa)    
Predicted Functional Partners:
AFE_0760
Conserved hypothetical protein; Identified by similarity to PIR:A64695; match to protein family HMM PF01863.
      
 0.457
AFE_3118
Pyridine nucleotide-disulfide oxidoreductase; Identified by similarity to SP:Q9R112; match to protein family HMM PF07992.
      
 0.446
AFE_2449
Conserved hypothetical protein; Identified by similarity to PIR:B75601; match to protein family HMM PF00462; match to protein family HMM PF05768.
      
 0.444
AFE_0286
Identified by match to protein family HMM PF00916.
      
 0.442
AFE_0875
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
 
  
 0.437
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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