STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0882Flavin monoamine oxidase family protein; Identified by similarity to SP:P40974; match to protein family HMM PF01266. (387 aa)    
Predicted Functional Partners:
AFE_2534
Identified by match to protein family HMM PF00850.
   
 0.937
AFE_0881
Conserved hypothetical protein; Identified by similarity to GB:BAC62652.1.
 
     0.890
AFE_0883
Conserved hypothetical protein; Identified by similarity to GB:BAC19717.1.
       0.773
AFE_0942
DNA helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434.
    
 0.748
AFE_1371
Helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.
    
 0.748
serA
D-3-phosphoglycerate dehydrogenase; Identified by similarity to SP:P35136; match to protein family HMM PF00389; match to protein family HMM PF01842; match to protein family HMM PF02826; match to protein family HMM TIGR01327; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 
 0.622
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
  
 0.579
AFE_1499
ATPase, AAA family; Identified by match to protein family HMM PF00004.
  
    0.521
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.520
AFE_1502
Ankyrin repeat protein/rhodanese-like domain protein; Identified by match to protein family HMM PF00023; match to protein family HMM PF00581.
  
 
 
 0.455
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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