Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0919Conserved hypothetical protein; Identified by similarity to GB:CAD14235.1. (213 aa)    
Predicted Functional Partners:
AFE_0918
Identified by match to protein family HMM PF01569.
 
     0.791
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.664
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.638
AFE_2019
Conserved domain protein.
  
     0.634
AFE_2169
Outer membrane toxin secretion efflux protein, putative; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
     0.543
AFE_2935
TonB-dependent receptor; Identified by match to protein family HMM PF00593.
  
     0.536
AFE_0920
Metal ion transporter, NRAMP family.
 
     0.535
AFE_3099
Hypothetical protein; Identified by glimmer; putative.
  
     0.500
AFE_2352
Conserved hypothetical protein; Identified by similarity to GB:BAC47910.1; match to protein family HMM PF00891; match to protein family HMM PF08241; match to protein family HMM PF08242.
  
     0.467
AFE_1002
Conserved hypothetical protein; Identified by similarity to GB:AAM08041.1.
  
     0.463
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.