Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0920Metal ion transporter, NRAMP family. (456 aa)    
Predicted Functional Partners:
AFE_0921
Hypothetical protein; Identified by glimmer; putative.
       0.757
AFE_0922
Drug resistance transporter, EmrB/QacA family; Identified by match to protein family HMM PF07690.
       0.757
AFE_2018
Conserved hypothetical protein; Identified by similarity to PIR:C70988.
  
     0.682
AFE_2307
Conserved domain protein; Identified by similarity to GB:AAO90256.1.
  
     0.682
AFE_3090
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.617
AFE_1498
ABC transporter, periplasmic substrate-binding protein, putative; Identified by match to protein family HMM PF01547.
  
     0.558
AFE_0719
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
 
     0.557
AFE_2330
Membrane protein, putative; Identified by match to protein family HMM PF03988.
  
     0.552
AFE_1716
GTP-binding protein.
  
  
  0.546
AFE_0919
Conserved hypothetical protein; Identified by similarity to GB:CAD14235.1.
 
     0.535
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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