Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glnDprotein-P-II uridylyltransferase; Identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF08335; match to protein family HMM TIGR01693. (862 aa)    
Predicted Functional Partners:
glnB-2
Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P05826; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 
 0.961
glnB-1
Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P05826; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 
 0.956
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
   
 0.919
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
    0.819
sfsA
Sugar fermentation stimulation protein; Identified by match to protein family HMM PF03749; match to protein family HMM TIGR00230; Belongs to the SfsA family.
       0.738
glnA
Glutamine synthetase, type I; Identified by similarity to SP:P06711; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.
 
   
 0.737
AFE_0927
glutamyl-tRNA synthetase-related protein; Identified by match to protein family HMM PF00749.
       0.723
hflD
Conserved hypothetical protein; Identified by similarity to GB:AAM85366.1.
 
     0.687
glnK-2
Nitrogen regulatory protein P-II 2; Identified by similarity to SP:P38504; match to protein family HMM PF00543.
 
 
 
 0.679
glnK-1
Nitrogen regulatory protein P-II 2; Identified by similarity to SP:P38504; match to protein family HMM PF00543; Belongs to the P(II) protein family.
 
 
 
 0.632
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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