Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hoxWHydrogenase maturation protease. (172 aa)    
Predicted Functional Partners:
hoxF
[NiFe] hydrogenase, beta subunit, putative; Identified by similarity to GB:BAC00528.1; match to protein family HMM PF00037.
 
   
 0.968
hoxH
[NiFe] hydrogenase, alpha subunit, putative; Identified by similarity to GB:BAC00531.1; match to protein family HMM PF00374.
 
  
 0.957
hoxY
[NiFe] hydrogenase, delta subunit, putative; Identified by similarity to GB:BAC00530.1; match to protein family HMM PF01058.
 
  
 0.954
hoxU
[NiFe] hydrogenase, gamma subunit, putative; Identified by similarity to GB:BAC00529.1; match to protein family HMM PF00175; match to protein family HMM PF00970.
 
    0.942
AFE_0935
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_0941
Murein transglycosylase, putative; Identified by similarity to SP:P03810; match to protein family HMM PF01464.
   
   0.582
hyfG
Hydrogenase-4, G subunit; Identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346.
  
  
 0.521
sreB
Sulfur reductase, iron-sulfur binding subunit; Identified by similarity to GB:CAC86938.1; match to protein family HMM PF00037.
  
  
 0.506
hup
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
      
 0.461
sreC
Sulfur reductase, membrane subunit, putative; Identified by match to protein family HMM PF03916.
     
 0.454
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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