Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0941Murein transglycosylase, putative; Identified by similarity to SP:P03810; match to protein family HMM PF01464. (639 aa)    
Predicted Functional Partners:
hoxW
Hydrogenase maturation protease.
   
   0.582
hoxY
[NiFe] hydrogenase, delta subunit, putative; Identified by similarity to GB:BAC00530.1; match to protein family HMM PF01058.
       0.572
hoxU
[NiFe] hydrogenase, gamma subunit, putative; Identified by similarity to GB:BAC00529.1; match to protein family HMM PF00175; match to protein family HMM PF00970.
       0.572
hoxF
[NiFe] hydrogenase, beta subunit, putative; Identified by similarity to GB:BAC00528.1; match to protein family HMM PF00037.
       0.572
AFE_1007
Transglycosylase, putative; Identified by match to protein family HMM PF01464.
  
   
 0.561
hoxH
[NiFe] hydrogenase, alpha subunit, putative; Identified by similarity to GB:BAC00531.1; match to protein family HMM PF00374.
       0.557
AFE_0935
Hypothetical protein; Identified by glimmer; putative.
       0.548
AFE_3189
Conserved domain protein; Identified by similarity to GB:CAD18424.1.
  
     0.547
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
    0.484
AFE_1568
Methyltransferase, putative; Identified by match to protein family HMM PF02086.
  
 
   0.469
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.