Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0949Conserved hypothetical protein; Identified by similarity to GB:AAO57577.1. (154 aa)    
Predicted Functional Partners:
AFE_0950
Oxidoreductase, GMC family; Identified by match to protein family HMM PF00732; match to protein family HMM PF01266.
       0.773
AFE_0951
Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
       0.682
AFE_1029
Hypothetical protein; Identified by glimmer; putative.
  
     0.608
AFE_0952
Hypothetical protein; Identified by glimmer; putative.
       0.540
AFE_3227
Hypothetical protein; Identified by glimmer; putative.
  
     0.523
AFE_0953
Conserved domain protein.
       0.514
cydB
Cytochrome d ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203.
       0.504
AFE_1786
Conserved hypothetical protein; Identified by similarity to GB:CAD16844.1.
  
     0.462
AFE_3216
Conserved hypothetical protein; Identified by similarity to GB:AAN54046.1; match to protein family HMM PF08241; match to protein family HMM PF08242.
  
     0.450
AFE_3120
Membrane protein, putative.
  
     0.443
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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