Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0956Identified by match to protein family HMM PF00753. (291 aa)    
Predicted Functional Partners:
cydA
Cytochrome d ubiquinol oxidase, subunit I; Identified by similarity to SP:Q09049; match to protein family HMM PF01654.
       0.747
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
 
 
 
 0.609
cydB
Cytochrome d ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203.
       0.587
AFE_0953
Conserved domain protein.
       0.558
AFE_0952
Hypothetical protein; Identified by glimmer; putative.
       0.531
AFE_0957
Sigma-54 dependent transcriptional regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF07728.
       0.526
AFE_2640
Hypothetical protein; Identified by glimmer; putative.
  
     0.470
tetH
Tetrathionate hydrolase; Catalyzes the hydrolysis of tetrathionate to generate elemental sulfur, thiosulfate and sulfate.
      
 0.461
AFE_0959
Phospholipase/carboxylesterase; Identified by match to protein family HMM PF02230.
   
   0.433
AFE_0951
Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
       0.428
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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