Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0957Sigma-54 dependent transcriptional regulator; Identified by match to protein family HMM PF00158; match to protein family HMM PF07728. (451 aa)    
Predicted Functional Partners:
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.805
AFE_3137
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF02954.
  
   
 0.775
AFE_1802
Fructose-bisphosphate aldolase, putative; Identified by similarity to SP:P58315; match to protein family HMM PF01791.
    
   0.652
AFE_0026
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
   
 0.617
AFE_0959
Phospholipase/carboxylesterase; Identified by match to protein family HMM PF02230.
       0.594
AFE_0956
Identified by match to protein family HMM PF00753.
       0.526
cydA
Cytochrome d ubiquinol oxidase, subunit I; Identified by similarity to SP:Q09049; match to protein family HMM PF01654.
       0.514
cbbR
Rubisco operon transcriptional regulator; Identified by similarity to SP:Q06610; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
      
 0.441
AFE_1595
Hypothetical protein; Identified by glimmer; putative.
     
 0.433
cydB
Cytochrome d ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203.
       0.418
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.