Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AFE_0971Pilin signal sequence domain protein; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. (188 aa)    
Predicted Functional Partners:
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
 
  
 0.982
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
 
  
 0.977
AFE_0970
Type IV pilin, putative; Identified by similarity to GB:AAB48595.1; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
     
 0.949
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
  
  
 0.842
AFE_0968
Hypothetical protein; Identified by glimmer; putative.
       0.783
AFE_0006
Pilus chaperone protein, putative; Identified by similarity to SP:P15319.
      
 0.750
AFE_2072
Conserved domain protein.
  
     0.654
AFE_0593
Chorismate lyase family protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
 
     0.616
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
 
  
 0.588
AFE_0737
Fimbrial assembly protein PilO, putative; Identified by match to protein family HMM PF04350.
 
  
 0.577
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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