Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pilCType IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482. (419 aa)    
Predicted Functional Partners:
AFE_0183
Type IV pilus assembly protein; Identified by similarity to SP:P45792; match to protein family HMM PF00437; match to protein family HMM PF05157; match to protein family HMM TIGR02538.
 
 
 0.976
AFE_1087
Type II/IV secretion system protein; Identified by match to protein family HMM PF00437.
 
 
 0.976
AFE_0739
Type IV pilus assembly protein PilM; Identified by similarity to PIR:S77726; match to protein family HMM TIGR01175.
 
 
 
 0.919
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.914
AFE_0735
Fimbrial assembly protein PilQ, putative; Identified by similarity to SP:P34750; match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM PF07660; match to protein family HMM TIGR02515.
 
 
 
 0.905
AFE_0416
Pilin, putative; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
 
  
 0.904
AFE_0970
Type IV pilin, putative; Identified by similarity to GB:AAB48595.1; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
  
 0.875
pilT-2
Twitching motility protein PilT; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420.
 
  
 0.864
AFE_0971
Pilin signal sequence domain protein; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
  
 0.842
AFE_1097
Conjugal transfer protein TraN, putative; Identified by similarity to SP:P24082.
  
  
 0.842
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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