Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_0973Type IV pilin biogenesis peptidase, putative; Identified by similarity to SP:P24213; match to protein family HMM PF01343; match to protein family HMM PF08496. (334 aa)    
Predicted Functional Partners:
moaE
Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.
       0.559
AFE_0977
Conserved hypothetical protein; Identified by match to protein family HMM PF04461; Belongs to the UPF0234 family.
       0.554
moaD
Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597.
       0.552
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
       0.519
AFE_0968
Hypothetical protein; Identified by glimmer; putative.
       0.519
AFE_0969
Type IV pilin, putative; Identified by match to protein family HMM TIGR02532.
       0.519
AFE_0970
Type IV pilin, putative; Identified by similarity to GB:AAB48595.1; match to protein family HMM PF07963; match to protein family HMM TIGR02532.
       0.519
AFE_0971
Pilin signal sequence domain protein; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
       0.519
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
       0.519
AFE_0978
roadblock/LC7 domain protein; Identified by similarity to GB:CAB71242.1; match to protein family HMM PF03259.
       0.510
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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