close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0977Conserved hypothetical protein; Identified by match to protein family HMM PF04461; Belongs to the UPF0234 family. (161 aa)    
Predicted Functional Partners:
moaD
Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597.
     
 0.817
moaE
Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.
       0.808
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
    0.725
AFE_0978
roadblock/LC7 domain protein; Identified by similarity to GB:CAB71242.1; match to protein family HMM PF03259.
       0.723
gcvT
Glycine cleavage system T protein; Identified by match to protein family HMM PF01571; match to protein family HMM PF08669; match to protein family HMM TIGR00528.
       0.723
gcvP
Glycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
       0.723
AFE_0982
Glycine dehydrogenase (decarboxylating), subunit 2.
       0.723
AFE_0973
Type IV pilin biogenesis peptidase, putative; Identified by similarity to SP:P24213; match to protein family HMM PF01343; match to protein family HMM PF08496.
       0.558
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.