Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_0993Identified by match to protein family HMM PF00753. (252 aa)    
Predicted Functional Partners:
phnJ
Phosphonate metabolism protein PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.
  
 
 0.927
AFE_0992
Hydrolase, TatD family; Identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010.
       0.805
AFE_0991
tRNA (guanosine-2'-O-)-methyltransferase, putative; Identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.736
AFE_0990
Hypothetical protein; Identified by glimmer; putative.
       0.695
ribF
Riboflavin biosynthesis protein RibF; Identified by similarity to SP:P08391; match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family.
      0.641
AFE_0989
Hypothetical protein; Identified by glimmer; putative.
       0.517
phnL
Phosphonate ABC transporter, ATP-binding protein PhnL; Identified by similarity to SP:P16679; match to protein family HMM PF00005; match to protein family HMM TIGR02324.
  
  
 0.505
AFE_2284
phnM protein, putative; Identified by similarity to SP:P16689; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318.
  
  
 0.452
phoR
Phosphate regulon sensor protein PhoR; Identified by similarity to SP:P08400; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM TIGR02966.
  
  
 0.417
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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