Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1002Conserved hypothetical protein; Identified by similarity to GB:AAM08041.1. (232 aa)    
Predicted Functional Partners:
AFE_1003
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1004
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1001
Hypothetical protein; Identified by glimmer; putative.
       0.681
AFE_0967
Type IV pilin biogenesis protein, putative; Identified by similarity to GB:AAQ58159.1.
  
     0.631
AFE_1000
BRO family protein; Identified by match to protein family HMM PF02498.
 
     0.551
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.516
AFE_1005
Hypothetical protein; Identified by glimmer; putative.
       0.509
AFE_3099
Hypothetical protein; Identified by glimmer; putative.
  
     0.496
AFE_3162
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
     0.490
AFE_0919
Conserved hypothetical protein; Identified by similarity to GB:CAD14235.1.
  
     0.463
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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