| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFE_2408 | csf4 | AFE_2408 | AFE_1037 | DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.802 |
| AFE_2408 | dnaN | AFE_2408 | AFE_0001 | DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.557 |
| AFE_2408 | polI | AFE_2408 | AFE_3094 | DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.861 |
| AFE_2408 | rpoA | AFE_2408 | AFE_0354 | DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.864 |
| AFE_3191 | csf4 | AFE_3191 | AFE_1037 | Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.802 |
| AFE_3191 | dnaN | AFE_3191 | AFE_0001 | Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.557 |
| AFE_3191 | polI | AFE_3191 | AFE_3094 | Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.855 |
| AFE_3191 | rpoA | AFE_3191 | AFE_0354 | Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.864 |
| csf1 | csf3 | AFE_1038 | AFE_1040 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | 0.934 |
| csf1 | csf4 | AFE_1038 | AFE_1037 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.876 |
| csf1 | recB | AFE_1038 | AFE_2932 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.475 |
| csf1 | ruvC | AFE_1038 | AFE_0060 | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.440 |
| csf3 | csf1 | AFE_1040 | AFE_1038 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | 0.934 |
| csf3 | csf4 | AFE_1040 | AFE_1037 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | 0.876 |
| csf3 | recB | AFE_1040 | AFE_2932 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.723 |
| csf3 | ruvC | AFE_1040 | AFE_0060 | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.723 |
| csf4 | AFE_2408 | AFE_1037 | AFE_2408 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | DEAD/DEAH box helicase, putative; Identified by match to protein family HMM PF00270; match to protein family HMM PF01896; match to protein family HMM PF04851. | 0.802 |
| csf4 | AFE_3191 | AFE_1037 | AFE_3191 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | Type III restriction-modification system, Res subunit; Identified by match to protein family HMM PF04851. | 0.802 |
| csf4 | csf1 | AFE_1037 | AFE_1038 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | CRISPR-associated protein, Csf1 family; Identified by match to protein family HMM TIGR03114. | 0.876 |
| csf4 | csf3 | AFE_1037 | AFE_1040 | CRISPR-associated DEAD/DEAH-box helicase Csf4; Identified by match to protein family HMM TIGR03117. | CRISPR-associated protein, Csf3 family; Identified by match to protein family HMM TIGR03116. | 0.876 |
