AFE_1066 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0367	AFE_0985	AFE_0367	AFE_0985	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	0.980
AFE_0367	AFE_1066	AFE_0367	AFE_1066	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Pilus assembly protein TraF, putative.	0.804
AFE_0367	AFE_3010	AFE_0367	AFE_3010	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.492
AFE_0367	msrA	AFE_0367	AFE_2946	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.725
AFE_0367	trxB	AFE_0367	AFE_0375	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.	0.477
AFE_0985	AFE_0367	AFE_0985	AFE_0367	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	0.980
AFE_0985	AFE_1066	AFE_0985	AFE_1066	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	Pilus assembly protein TraF, putative.	0.920
AFE_0985	AFE_3010	AFE_0985	AFE_3010	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.558
AFE_0985	msrA	AFE_0985	AFE_2946	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.420
AFE_0985	trxB	AFE_0985	AFE_0375	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.	0.900
AFE_1066	AFE_0367	AFE_1066	AFE_0367	Pilus assembly protein TraF, putative.	AhpC/TSA family/glutaredoxin domain protein; Identified by match to protein family HMM PF00462; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR02190.	0.804
AFE_1066	AFE_0985	AFE_1066	AFE_0985	Pilus assembly protein TraF, putative.	Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.	0.920
AFE_1066	AFE_1067	AFE_1066	AFE_1067	Pilus assembly protein TraF, putative.	Pilus assembly protein TraH, putative; Identified by similarity to SP:P15069.	0.950
AFE_1066	AFE_1068	AFE_1066	AFE_1068	Pilus assembly protein TraF, putative.	Pilus assembly protein TraG, putative; Identified by similarity to GB:AAK61533.1.	0.947
AFE_1066	AFE_1081	AFE_1066	AFE_1081	Pilus assembly protein TraF, putative.	Conjugal transfer protein, putative; Identified by similarity to GB:AAD54048.1.	0.803
AFE_1066	AFE_1097	AFE_1066	AFE_1097	Pilus assembly protein TraF, putative.	Conjugal transfer protein TraN, putative; Identified by similarity to SP:P24082.	0.803
AFE_1066	AFE_3010	AFE_1066	AFE_3010	Pilus assembly protein TraF, putative.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.832
AFE_1066	dsbD	AFE_1066	AFE_0545	Pilus assembly protein TraF, putative.	Thiol:disulfide interchange protein DsbD; Identified by similarity to SP:P36655; match to protein family HMM PF02683.	0.919
AFE_1066	msrA	AFE_1066	AFE_2946	Pilus assembly protein TraF, putative.	Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.899
AFE_1066	trxB	AFE_1066	AFE_0375	Pilus assembly protein TraF, putative.	Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.	0.829