Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1073BRO family protein; Identified by match to protein family HMM PF02498. (313 aa)    
Predicted Functional Partners:
AFE_1074
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_3021
ATPase; Displays ATPase and GTPase activities.
      
 0.724
AFE_1075
Conserved hypothetical protein.
       0.581
AFE_1071
Conserved hypothetical protein; Identified by similarity to GB:CAD84733.1.
       0.570
AFE_1072
Conserved hypothetical protein; Identified by match to protein family HMM PF08808.
       0.570
AFE_1076
Hypothetical protein; Identified by glimmer; putative.
       0.505
AFE_1077
Hypothetical protein; Identified by glimmer; putative.
       0.505
traL
Type IV conjugative transfer system protein TraL; Identified by similarity to GB:AAM08076.1; match to protein family HMM TIGR02762.
       0.505
traE
Type IV conjugative transfer system protein TraE; Identified by similarity to GB:AAL27019.1; match to protein family HMM TIGR02761.
       0.505
traK
TraK lipoprotein, putative; Identified by similarity to GB:AAM90706.1.
       0.505
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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