Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1087Type II/IV secretion system protein; Identified by match to protein family HMM PF00437. (396 aa)    
Predicted Functional Partners:
pilC
Type IV pilus biogenesis protein PilC; Identified by similarity to SP:P45793; match to protein family HMM PF00482.
 
 
 0.976
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.852
AFE_0416
Pilin, putative; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532.
  
 
 0.806
AFE_1097
Conjugal transfer protein TraN, putative; Identified by similarity to SP:P24082.
  
 
 0.800
traC
type-IV secretion system protein TraC; Identified by similarity to SP:P18004; match to protein family HMM TIGR02746.
  
    0.777
AFE_1090
Hypothetical protein; Identified by glimmer; putative.
       0.777
AFE_1088
Thiol:disulfide interchange protein, DsbA family; Identified by similarity to SP:Q44504.
       0.773
AFE_1091
Conjugation signal peptidase TraF, putative; Identified by similarity to SP:P26844; similarity to GB:AAL59670.1.
       0.773
AFE_0738
Type IV pilus biogenesis protein PilN; Identified by match to protein family HMM PF05137.
  
 
 0.706
AFE_1915
Type IV pilus assembly protein PilZ, putative; Identified by similarity to PIR:B59241; match to protein family HMM PF07238.
    
 
 0.684
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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