Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1093Hypothetical protein; Identified by glimmer; putative. (322 aa)    
Predicted Functional Partners:
AFE_1087
Type II/IV secretion system protein; Identified by match to protein family HMM PF00437.
       0.521
traC
type-IV secretion system protein TraC; Identified by similarity to SP:P18004; match to protein family HMM TIGR02746.
       0.521
AFE_1090
Hypothetical protein; Identified by glimmer; putative.
       0.521
AFE_1088
Thiol:disulfide interchange protein, DsbA family; Identified by similarity to SP:Q44504.
       0.511
AFE_1091
Conjugation signal peptidase TraF, putative; Identified by similarity to SP:P26844; similarity to GB:AAL59670.1.
       0.511
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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