Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1145Tyrosine recombinase, phage integrase family; Identified by similarity to SP:P46352; similarity to SP:Q8YJP2; match to protein family HMM PF00589; Belongs to the 'phage' integrase family. (301 aa)    
Predicted Functional Partners:
AFE_0508
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589.
  
     0.773
AFE_0834
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589.
  
     0.773
AFE_2398
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589.
  
     0.773
AFE_1146
Hypothetical protein; Identified by glimmer; putative.
       0.489
AFE_1147
Hypothetical protein; Identified by glimmer; putative.
       0.477
AFE_1148
Hypothetical protein; Identified by glimmer; putative.
       0.465
AFE_1719
Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
  
    0.454
AFE_1556
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589.
  
     0.445
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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