Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1218Conserved domain protein; Identified by similarity to PIR:A97990. (238 aa)    
Predicted Functional Partners:
AFE_1217
uracil-DNA glycosylase, family 4; Identified by match to protein family HMM PF03167.
       0.773
AFE_1216
Hypothetical protein; Identified by glimmer; putative.
       0.675
AFE_1547
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.634
AFE_0966
Conserved hypothetical protein.
  
     0.629
AFE_2019
Conserved domain protein.
  
     0.617
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.524
AFE_0458
Rare lipoprotein B, putative; Identified by similarity to SP:P10101.
  
     0.521
AFE_1301
Hypothetical protein; Identified by glimmer; putative.
  
     0.517
AFE_0268
Conserved domain protein; Identified by similarity to GB:CAD79002.1.
  
     0.491
AFE_1215
ISAfe8, transposase; Identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766.
       0.485
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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