AFE_1226 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_0687	AFE_1226	AFE_0687	AFE_1226	Hypothetical protein; Identified by glimmer; putative.	Identified by match to protein family HMM PF02463.	0.460
AFE_0687	AFE_3010	AFE_0687	AFE_3010	Hypothetical protein; Identified by glimmer; putative.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.536
AFE_1225	AFE_1226	AFE_1225	AFE_1226	Hypothetical protein; Identified by glimmer; putative.	Identified by match to protein family HMM PF02463.	0.631
AFE_1225	AFE_1227	AFE_1225	AFE_1227	Hypothetical protein; Identified by glimmer; putative.	Identified by match to protein family HMM PF00149.	0.631
AFE_1225	AFE_1228	AFE_1225	AFE_1228	Hypothetical protein; Identified by glimmer; putative.	Hypothetical protein; Identified by glimmer; putative.	0.418
AFE_1226	AFE_0687	AFE_1226	AFE_0687	Identified by match to protein family HMM PF02463.	Hypothetical protein; Identified by glimmer; putative.	0.460
AFE_1226	AFE_1225	AFE_1226	AFE_1225	Identified by match to protein family HMM PF02463.	Hypothetical protein; Identified by glimmer; putative.	0.631
AFE_1226	AFE_1227	AFE_1226	AFE_1227	Identified by match to protein family HMM PF02463.	Identified by match to protein family HMM PF00149.	0.955
AFE_1226	AFE_1228	AFE_1226	AFE_1228	Identified by match to protein family HMM PF02463.	Hypothetical protein; Identified by glimmer; putative.	0.499
AFE_1226	AFE_2534	AFE_1226	AFE_2534	Identified by match to protein family HMM PF02463.	Identified by match to protein family HMM PF00850.	0.491
AFE_1226	AFE_3010	AFE_1226	AFE_3010	Identified by match to protein family HMM PF02463.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.509
AFE_1226	gyrB	AFE_1226	AFE_0003	Identified by match to protein family HMM PF02463.	DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.494
AFE_1226	parE	AFE_1226	AFE_2029	Identified by match to protein family HMM PF02463.	DNA topoisomerase IV, subunit B; Identified by similarity to SP:P20083; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF02518.	0.494
AFE_1226	recQ	AFE_1226	AFE_2194	Identified by match to protein family HMM PF02463.	ATP-dependent DNA helicase RecQ; Identified by similarity to SP:P15043; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.506
AFE_1226	scpA	AFE_1226	AFE_1790	Identified by match to protein family HMM PF02463.	Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.702
AFE_1227	AFE_1225	AFE_1227	AFE_1225	Identified by match to protein family HMM PF00149.	Hypothetical protein; Identified by glimmer; putative.	0.631
AFE_1227	AFE_1226	AFE_1227	AFE_1226	Identified by match to protein family HMM PF00149.	Identified by match to protein family HMM PF02463.	0.955
AFE_1227	AFE_1228	AFE_1227	AFE_1228	Identified by match to protein family HMM PF00149.	Hypothetical protein; Identified by glimmer; putative.	0.499
AFE_1227	AFE_3010	AFE_1227	AFE_3010	Identified by match to protein family HMM PF00149.	Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.	0.605
AFE_1227	recQ	AFE_1227	AFE_2194	Identified by match to protein family HMM PF00149.	ATP-dependent DNA helicase RecQ; Identified by similarity to SP:P15043; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.938