Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1233Hypothetical protein; Identified by glimmer; putative. (151 aa)    
Predicted Functional Partners:
AFE_1232
Hypothetical protein; Identified by glimmer; putative.
       0.773
AFE_1234
Lipoprotein, putative; Identified by match to protein family HMM PF05433.
       0.773
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
   
    0.757
AFE_1235
Lipoprotein, putative.
       0.675
AFE_1236
Hypothetical protein; Identified by glimmer; putative.
       0.656
AFE_1237
Hypothetical protein; Identified by glimmer; putative.
       0.630
ligA-2
DNA ligase, NAD-dependent, putative; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.414
AFE_1229
EAL domain protein; Identified by match to protein family HMM PF00563.
       0.410
AFE_1231
Hypothetical protein; Identified by glimmer; putative.
       0.410
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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