Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1275Conserved hypothetical protein. (303 aa)    
Predicted Functional Partners:
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 
 0.823
AFE_1292
Conserved hypothetical protein; Identified by similarity to GB:AAL59705.1.
 
    0.808
AFE_1274
Hypothetical protein; Identified by glimmer; putative.
       0.777
AFE_1095
Pilus assembly protein TraW, putative; Identified by similarity to SP:P18472.
  
   
 0.764
AFE_1068
Pilus assembly protein TraG, putative; Identified by similarity to GB:AAK61533.1.
  
     0.744
traE
Type IV conjugative transfer system protein TraE; Identified by similarity to GB:AAL27019.1; match to protein family HMM TIGR02761.
  
     0.742
AFE_1066
Pilus assembly protein TraF, putative.
  
 
   0.731
AFE_1097
Conjugal transfer protein TraN, putative; Identified by similarity to SP:P24082.
  
     0.728
AFE_1096
Conjugal transfer protein TraU, putative; Identified by similarity to SP:P18471.
  
     0.714
AFE_1067
Pilus assembly protein TraH, putative; Identified by similarity to SP:P15069.
  
     0.691
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
Server load: low (16%) [HD]