Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_1296Transcriptional regulator, LysR family; Identified by similarity to SP:Q47083; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. (320 aa)    
Predicted Functional Partners:
AFE_1295
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF02954.
  
    0.605
AFE_2875
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.524
AFE_1293
Hypothetical protein; Identified by glimmer; putative.
       0.505
AFE_1294
Hypothetical protein; Identified by glimmer; putative.
       0.505
AFE_1297
Cobalamin biosynthesis protein, CobS family; Identified by match to protein family HMM PF07728.
  
    0.478
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
     
 0.445
AFE_2148
DNA-binding protein, putative; Identified by similarity to GB:AAO56394.1; match to protein family HMM PF01381; match to protein family HMM PF07883.
  
  
 0.421
ppx
Exopolyphosphatase; Identified by similarity to SP:Q9ZN70; match to protein family HMM PF02541.
  
     0.414
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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