Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1301Hypothetical protein; Identified by glimmer; putative. (339 aa)    
Predicted Functional Partners:
cysNC
Sulfate adenylate transferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.991
cysC
Sulfate adenylyltransferase, putative/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.962
cysN
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.756
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.750
AFE_3220
Hypothetical protein; Identified by glimmer; putative.
  
     0.706
AFE_1855
Membrane protein, putative; Identified by match to protein family HMM PF07690.
  
     0.697
AFE_2298
TonB-dependent receptor; Identified by match to protein family HMM PF00593; match to protein family HMM PF07715.
  
     0.693
AFE_1615
DNA primase TraC; Identified by similarity to SP:P27189; match to protein family HMM PF08401.
 
     0.678
AFE_1726
Conjugal transfer protein TraF, putative; Identified by similarity to SP:Q44350.
  
     0.650
AFE_1798
Membrane protein, putative.
  
     0.634
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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