Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1340Tyrosine-protein kinase, putative; Identified by similarity to SP:P38134; match to protein family HMM PF02706. (820 aa)    
Predicted Functional Partners:
AFE_1339
Polysaccharide biosynthesis/export domain protein; Identified by match to protein family HMM PF02563.
 
 
 0.995
AFE_2975
Capsule polysaccharide export protein, BexD/CtrA/VexA family; Identified by similarity to SP:P22236; match to protein family HMM PF02563.
 
 
 0.973
AFE_1341
Protein-tyrosine phosphatase, putative; Identified by similarity to SP:P39852.
 
  
 0.943
AFE_1370
Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.
 
  
 0.930
AFE_0073
Undecaprenyl-phosphate galactosephosphotransferase; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.
 
  
 0.923
galE
UDP-glucose 4-epimerase; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
     
 0.867
AFE_1343
UDP-glucose 6-dehydrogenase; Identified by similarity to SP:O54068; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026.
     
 0.812
AFE_1344
Polysaccharide biosynthesis protein; Identified by match to protein family HMM PF01943.
 
  
 0.804
AFE_1346
Glycosyl transferase, group 2 family protein; Identified by match to protein family HMM PF00535.
 
  
 0.752
AFE_1338
Identified by match to protein family HMM PF01569.
  
  
 0.670
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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