Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1367Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255. (75 aa)    
Predicted Functional Partners:
AFE_1368
Conserved hypothetical protein; Identified by similarity to PIR:AG2077.
 
   
 0.985
vapC-4
PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
 
     0.731
parE
DNA topoisomerase IV, subunit B; Identified by similarity to SP:P20083; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF02518.
      
 0.713
AFE_2414
Conserved hypothetical protein; Identified by similarity to GB:AAN70104.1; match to protein family HMM PF04365.
  
     0.677
AFE_1371
Helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.
 
     0.637
AFE_1370
Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.
       0.615
AFE_1383
Conserved hypothetical protein; Identified by similarity to PIR:AF1935.
  
   
 0.598
AFE_0072
Conserved hypothetical protein; Identified by similarity to PIR:S76075.
  
     0.595
AFE_1384
Conserved hypothetical protein; Identified by similarity to GB:AAP44226.1; match to protein family HMM PF05973.
  
   
 0.576
AFE_0582
Conserved hypothetical protein; Identified by similarity to GB:AAL62784.1.
  
     0.549
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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