AFE_1368 protein (Acidithiobacillus ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1366	AFE_1367	AFE_1366	AFE_1367	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	0.484
AFE_1366	AFE_1368	AFE_1366	AFE_1368	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	0.480
AFE_1366	AFE_1370	AFE_1366	AFE_1370	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.	0.907
AFE_1367	AFE_1366	AFE_1367	AFE_1366	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.484
AFE_1367	AFE_1368	AFE_1367	AFE_1368	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	0.985
AFE_1367	AFE_1370	AFE_1367	AFE_1370	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.	0.615
AFE_1367	AFE_1371	AFE_1367	AFE_1371	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	0.637
AFE_1367	AFE_1383	AFE_1367	AFE_1383	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Conserved hypothetical protein; Identified by similarity to PIR:AF1935.	0.598
AFE_1367	AFE_1384	AFE_1367	AFE_1384	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	Conserved hypothetical protein; Identified by similarity to GB:AAP44226.1; match to protein family HMM PF05973.	0.576
AFE_1367	parE	AFE_1367	AFE_2029	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	DNA topoisomerase IV, subunit B; Identified by similarity to SP:P20083; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF02518.	0.713
AFE_1367	vapC-4	AFE_1367	AFE_1369	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.731
AFE_1368	AFE_1366	AFE_1368	AFE_1366	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.480
AFE_1368	AFE_1367	AFE_1368	AFE_1367	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.	0.985
AFE_1368	AFE_1370	AFE_1368	AFE_1370	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.	0.615
AFE_1368	AFE_1371	AFE_1368	AFE_1371	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	0.626
AFE_1368	AFE_1383	AFE_1368	AFE_1383	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Conserved hypothetical protein; Identified by similarity to PIR:AF1935.	0.535
AFE_1368	AFE_1384	AFE_1368	AFE_1384	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	Conserved hypothetical protein; Identified by similarity to GB:AAP44226.1; match to protein family HMM PF05973.	0.510
AFE_1368	parE	AFE_1368	AFE_2029	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	DNA topoisomerase IV, subunit B; Identified by similarity to SP:P20083; match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF02518.	0.713
AFE_1368	vapC-4	AFE_1368	AFE_1369	Conserved hypothetical protein; Identified by similarity to PIR:AG2077.	PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.	0.663
AFE_1370	AFE_1366	AFE_1370	AFE_1366	Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.	Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by similarity to SP:P29956; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family.	0.907