Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
vapC-4PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (259 aa)    
Predicted Functional Partners:
AFE_1370
Undecaprenyl-phosphate galactosephosphotransferase, putative; Identified by similarity to SP:P26406; match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025.
       0.773
AFE_1367
Conserved hypothetical protein; Identified by similarity to PIR:AF2077; match to protein family HMM PF04255.
 
     0.731
AFE_1371
Helicase, SNF2/RAD54 family; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.
       0.705
AFE_1368
Conserved hypothetical protein; Identified by similarity to PIR:AG2077.
 
     0.663
AFE_2888
PIN domain protein; Identified by match to protein family HMM PF01850.
  
     0.633
AFE_2984
PIN domain protein; Identified by match to protein family HMM PF01850.
  
     0.486
AFE_1365
HNH endonuclease domain protein; Identified by match to protein family HMM PF01844.
 
     0.430
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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