Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (529 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase complex, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.998
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by similarity to SP:P30011; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
  
 0.995
AFE_1544
Pyrophosphorylase, putative; Identified by similarity to SP:P59245; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR01334; Belongs to the NadC/ModD family.
 
  
 0.946
argG
Argininosuccinate synthase; Identified by similarity to SP:Q9HY84; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.914
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.913
asnB
Asparagine synthase (glutamine-hydrolyzing); Identified by similarity to SP:P54420; match to protein family HMM PF00310; match to protein family HMM PF00733; match to protein family HMM TIGR01536.
     
 0.909
pyrB
Aspartate carbamoyltransferase; Identified by similarity to SP:Q59711; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
  0.901
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
      0.841
aspC
Aspartate aminotransferase; Identified by similarity to SP:P23034; match to protein family HMM PF00155.
   
 
 0.833
AFE_3000
Identified by similarity to SP:Q60176; match to protein family HMM PF00056.
    
 0.832
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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