Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AFE_1395Conserved domain protein; Identified by similarity to GB:AAQ59731.1. (220 aa)    
Predicted Functional Partners:
rpoE
RNA polymerase sigma-E factor; Identified by similarity to SP:P34086; match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR02939; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.993
AFE_1396
Serine protease, DO/DeqQ family; Identified by similarity to SP:P09376; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
 
 0.862
sspB
Identified by similarity to SP:P25663; match to protein family HMM PF04386.
    
 
 0.806
AFE_1646
Serine protease, DO/DeqQ family; Identified by similarity to GB:AAK01318.1; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037.
  
 
 0.755
AFE_2849
Serine protease, DO/DeqQ family; Identified by similarity to GB:AAN67052.1; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family.
  
 
 0.755
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.593
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.411
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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