Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AFE_1396Serine protease, DO/DeqQ family; Identified by similarity to SP:P09376; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037; Belongs to the peptidase S1C family. (479 aa)    
Predicted Functional Partners:
AFE_1646
Serine protease, DO/DeqQ family; Identified by similarity to GB:AAK01318.1; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037.
  
  
 
0.905
AFE_1395
Conserved domain protein; Identified by similarity to GB:AAQ59731.1.
  
 
 0.862
AFE_2762
TPR domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
 
 
 0.821
AFE_1211
TPR domain/sulfotransferase domain protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF00685; match to protein family HMM PF07719; match to protein family HMM PF07721.
  
 
 0.761
AFE_0651
Hypothetical protein; Identified by glimmer; putative.
    
 0.615
AFE_3010
Polyketide synthase, type I, putative; Identified by similarity to GB:AAK26474.1; match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM PF08240; match to protein family HMM PF08659.
  
 0.591
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
  
 0.583
lepB
Signal peptidase I; Identified by similarity to SP:P26844; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
 
   
 0.566
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
   
 0.536
rpoE
RNA polymerase sigma-E factor; Identified by similarity to SP:P34086; match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; match to protein family HMM TIGR02939; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.534
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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