AFE_1458 protein (Acidithiobacillus ferrooxidans)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Acidithiobacillus ferrooxidans

NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFE_1453	AFE_1457	AFE_1453	AFE_1457	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	0.815
AFE_1453	AFE_1458	AFE_1453	AFE_1458	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	Pleiotropic regulatory protein, putative; Identified by similarity to SP:P15263; match to protein family HMM PF01041; match to protein family HMM PF01212; Belongs to the DegT/DnrJ/EryC1 family.	0.640
AFE_1453	accA	AFE_1453	AFE_1462	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.588
AFE_1453	dnaE	AFE_1453	AFE_1461	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	0.624
AFE_1453	fabZ	AFE_1453	AFE_1455	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.	0.871
AFE_1453	lpxA	AFE_1453	AFE_1456	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	acyl-(acyl-carrier-protein)-UDP-N- acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.863
AFE_1453	lpxB	AFE_1453	AFE_1459	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	Lipid A disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.677
AFE_1453	lpxD	AFE_1453	AFE_1454	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	0.961
AFE_1453	rnhB	AFE_1453	AFE_1460	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.648
AFE_1453	tilS	AFE_1453	AFE_1464	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.	0.574
AFE_1457	AFE_1453	AFE_1457	AFE_1453	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	Outer membrane protein, OmpH family; Identified by match to protein family HMM PF03938.	0.815
AFE_1457	AFE_1458	AFE_1457	AFE_1458	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	Pleiotropic regulatory protein, putative; Identified by similarity to SP:P15263; match to protein family HMM PF01041; match to protein family HMM PF01212; Belongs to the DegT/DnrJ/EryC1 family.	0.927
AFE_1457	accA	AFE_1457	AFE_1462	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.543
AFE_1457	dnaE	AFE_1457	AFE_1461	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	DNA polymerase III, alpha subunit; Identified by similarity to SP:P10443; match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.	0.624
AFE_1457	fabZ	AFE_1457	AFE_1455	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.	0.805
AFE_1457	lpxA	AFE_1457	AFE_1456	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	acyl-(acyl-carrier-protein)-UDP-N- acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.833
AFE_1457	lpxB	AFE_1457	AFE_1459	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	Lipid A disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.735
AFE_1457	lpxD	AFE_1457	AFE_1454	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.	0.832
AFE_1457	rnhB	AFE_1457	AFE_1460	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.648
AFE_1457	tilS	AFE_1457	AFE_1464	Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408; match to protein family HMM PF02894.	tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.	0.570