Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (637 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase; Identified by similarity to SP:O34858; match to protein family HMM PF00206; match to protein family HMM TIGR00838.
     
 0.828
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
    
 0.696
AFE_2176
Peptidyl-arginine deiminase, Porphyromonas-type; Identified by match to protein family HMM PF04371; Belongs to the agmatine deiminase family.
 
   
 0.618
AFE_1469
Identified by match to protein family HMM PF02562.
       0.590
AFE_1468
Antioxidant, AhpC/Tsa family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
       0.583
AFE_2526
Hydrolase, carbon-nitrogen family; Identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381.
 
  
 0.455
AFE_1467
Transcriptional regulator, Fur family; Belongs to the Fur family.
       0.417
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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