Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFE_1472Identified by match to protein family HMM PF01557. (227 aa)    
Predicted Functional Partners:
AFE_1474
Glutathione S-transferase, putative; Identified by similarity to SP:P39100; match to protein family HMM PF02798.
 
  
 0.860
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.823
AFE_1476
Conserved hypothetical protein; Identified by similarity to GB:AAA64729.1.
 
     0.793
AFE_1475
Hypothetical protein; Identified by glimmer; putative.
       0.777
AFE_1473
Hypothetical protein; Identified by glimmer; putative.
       0.773
fixX
Ferredoxin-like protein; Could be a 3Fe-4S cluster-containing protein.
       0.699
fixC
fixC protein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.
       0.699
fixB
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P26483; match to protein family HMM PF00766; match to protein family HMM PF01012.
  
    0.675
AFE_1470
Hypothetical protein; Identified by glimmer; putative.
       0.665
fixA
Electron transfer flavoprotein, beta subunit; Identified by similarity to SP:P53577; match to protein family HMM PF01012.
  
    0.636
Your Current Organism:
Acidithiobacillus ferrooxidans
NCBI taxonomy Id: 243159
Other names: A. ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans ATCC 23270, Acidithiobacillus ferrooxidans str. ATCC 23270
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